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This process, along with GCL inhibition and the formation of mixed disulfides between GSH and protein sulfhydryl, concurred to a steady-state decrement of free GSH concentration and, consequently, to an intracellular redox state shift toward more oxidizing conditions, which could be required for avoiding fast reduction of oxidized cysteines allowing the upstream ROS-induced autophagic stimulus to be propagated
Medizinisch / wissenschaftlich wird GHK-Cu als Signal- und Carrier-Peptid betrachtet, das in regenerative Prozesse eingreift und deshalb auch in der Wundheilungs- und Altersforschung relevant ist
