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In the present study, the significant reductions of liver and plasma GSH (Table 3) and cystathionine concentrations (Table 2), in addition to the significant correlation between these two compounds, suggested that modulation of the methyl balance and the consequent reduction of Hcy can down-regulate the trans-sulfuration pathway in a dose-dependent response

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J Appl Microbiol 107:11401148 Wang S, Dougherty EJ, Danner RL (2016) PPAR signaling and emerging opportunities for improved therapeutics

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