One of the biggest concerns among healthcare professionals is that once the peptide promotes melanogenesis (the production of melanin) theres no way to stop the continuing production of melanin
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The most common were nausea (28.6%, 38.4% and 42.4% vs 14.8%), diarrhoea (25.2%, 34.1% and 32.0% vs 13.5%), constipation (23.8%, 25.9% and 26.1% vs 10.9%), vomiting (10.6%, 22.8% and 25.3% vs 4.8%), and upper respiratory tract infection (14.2%, 12.2% and 13.1% vs 11.6%)
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Sugimoto M, Furui S, Suzuki Y (1997) Molecular cloning and characterization of a cDNA encoding putative phospholipid hydroperoxide glutathione from spinach