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Becker U, Gronbaek M, Johansen D, Sorensen TI

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Aging and chronic ailments like diabetes decrease the ability of the kidneys to recover from injuries, resulting in chronic kidney disease (CKD)

Furthermore, SUN significantly reduced activity of AMPK following treatment with the AMPK activator, AICAR, as evidenced by decreased P-ACC2 protein expression and the degree of inhibition was parallel to that seen with the AMPK inhibitor, compound C [17]