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Significant ALDH3A1 upregulation in HCC and hepatocellular adenomas serves as a biomarker of Wnt/-catenin signaling pathway activation, although no correlation has been found between ALDH3A1 expression and patient prognosis

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Robbins PD, Jurk D, Khosla S, Kirkland JL, LeBrasseur NK, Miller JD, Passos JF, Pignolo RJ, Tchkonia T, Niedernhofer LJ (2021) Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span

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HCC / Risk Adjustment (v28) Diabetes mellitus is among the most significant conditions in Medicare Advantage (MA) risk adjustment under CMS-HCC Model V28, which became fully operative for payment year 2026 (eliminating the 20242025 V24/V28 blend)

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