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For this interaction to occur, the structural requirement in the enzyme is the presence of a nucleophilic amino acid side-chain close to the glutathione-docking motif and in a crucial position to interact with the electrophilic motif of glutathione acrylate, as shown in Scheme 9

The hearing of the noise-exposed mice remained within the normal range, with no apparent impairment

& Evans-Molina, C

Additionally, the brightening effects of Vitamin C are significant

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