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Figure 3 represents the overall mechanism of polyphenol in AD

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Membranes were solubilized in resuspension buffer (50 mM Tris-Cl pH 7.0, 300 mM NaCl, 0.5% 2,2-didecylpropane-1,3-bis--D-maltopyranoside (LMNG)/0.05% cholesteryl hemisuccinate (CHS) supplemented with protease inhibitor as described above) at a ratio of 15 mL/g of membrane at 4 C for 4 h

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