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(1) Adolescence (1218 years): high sensitivity to high-sugar diets Although human studies investigating the gut microbiome in adolescents remain limited, the ongoing development of the gut-brain axis and the adolescent brain suggests that this population may be particularly susceptible to diet-induced depressive symptoms (320), The impact of high-sugar diets on metabolic and intestinal health In male C57BL/6J mice, consumption of a high-glucose diet (HGD) over a 12-week period induces hyperglycemia, glucose intolerance, dyslipidemia, and increased adipose deposition

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IGFR, Insulin-like growth factor receptor

6-Month Results: Improved confidence, better appetite control, and increased energy levels

I give a shout out to Kristen

Funding The project was supported by National Natural Science Foundation of China (82000842)