glp-1 bone density loss Agonists and Orthopedic Surgery: A Review of Their Impact on Metabolism, Wound Healing, and Surgical Outcomes Are GLP-1s Killing Your Bones?

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Ghozlan, M.N

These drugs also exert other GLP-1 effects, including reducing glucagon secretion, delaying gastric emptying, reducing food intake, improving cardiac ventricular function, and lowering blood pressure

by Jace A

We included patients who had been treated with an SGLT2i or GLP-1 RA for at least 6 months and analysed the efficacy, safety and cardio-renal outcomes 5 years after initiation of therapy

Subsequently, the sequence of GLP-1 was identified following the cloning of the glucagon cDNAs and genes, soon followed by the demonstration that GLP-1 potentiated glucose-dependent insulin secretion in cells, animals, and humans (comprehensively reviewed in Drucker, et al