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Apoptosis describes a programmed mode of cell death that is characterized by a series of biochemical events that ultimately lead to cell fragmentation into compact membrane-enclosed structures, called apoptotic bodies that are taken up by neighboring cells and phagocytes, preventing inflammation, and tissue damage (Taylor et al., 2008)

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Several studies examined the effects of glutathione on skin lightening and found that glutathione lowered participants melanin index scores

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1620 An open-label, single-arm trial study by Handog et al 21 used lozenges to prevent absorption by the gastrointestinal tract and found that the melanin index declined significantly in both sun-exposed and unexposed skin