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With regards to oral disorders, caries and periodontal diseases are multifactorial diseases of undoubted complexity and continue to be the two most widespread diseases in the world (137, 138)

Data Availability Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study

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Many people today face skin problems that can lead to depression and anxiety

For example, some people feel really awful if their Effexor is even an hour late