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ABSTRACT: Parkinsons disease (PD) is a progressive neurodegenerative disorder that stems from a deficiency of dopamine

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Studies have shown that oxidative glutamate toxicity in neurons lacking functional N-methyl-D-aspartate (NMDA) receptors may represent a component of the cellular death pathway induced by excitotoxicity

While gabapentin can significantly reduce nerve-related sciatica symptoms, it requires patience for gradual dose escalation and works best combined with physical therapy rather than as monotherapy

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