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Discontinuation might be a factor limiting neuroprotective benefits of GLP1 receptor agonists
In addition, the different distribution of SGLT2 and GLP-1R may be involved
doi:10.1073/pnas.2014879117 Pratt E, Ma X, Liu R, et al
, 2023 , 95 (1), e28393-e28393
Public Health 20 (4), 2868
Now their stomachs are paralyzed July 25, 2023 Facial lipoatrophy with semaglutide-related weight loss February 10, 2023 --------------------------------------- Glucagon-like peptide 1 (GLP-1) agonists are medications approved for treatment of diabetes that recently have also been used off label for weight loss.1 Studies have found increased risks of gastrointestinal adverse events (biliary disease,2 pancreatitis,3 bowel obstruction,4 and gastroparesis5) in patients with diabetes.2-5 Because such patients have higher baseline risk for gastrointestinal adverse events, risk in patients taking these drugs for other indications may differ
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