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These advantageous actions of the tested agents were accounted to their antioxidant, anti-inflammatory and anti-apoptotic properties, along with their abilities to modulate HMGB1/RAGE/JAK-2/STAT-3, PI3K/AKT/CREB/BDNF/TrkB, AMPK/SIRT-1/m-TOR and PERK/CHOP/GRP78/Bcl-2 hubs, as main contributors in the underlying pathophysiological mechanisms in MSG-induced ADHD-like behaviors (Graphical abstract)

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14] In November 2024, LumiTheras Valeda Light Delivery System received FDA authorization to treat dry AMD and its later stage, geographic atropy

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doi:10.1016/j.cofs.2016.02.002 [Elsevier] Hurrell R, Egli I

Mitophagy-related proteins Parkin, BNIP3, and NIX are all considered to have tumor-suppressive functions