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Tirzepatide commonly causes nausea, vomiting, diarrhea, and decreased appetite, particularly during dose escalation

2B depicts incorporation of labels from [U- 13 C3, 15 N1]l-cysteine into the detected metabolites in E

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In contrast, recent meta-analyses suggest that GLP-1 RA use does not increase the risk of pancreatitis and/or pancreatic cancer, compared to placebo and/or other treatments [101,102,103]