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While the dramatic physical transformations are widely celebrated, some patients have reported an unexpected and distressing side effect: sudden hair shedding

Diabetes 50: 609613

Tirzepatide (often (branded as Mounjaro or Zepbound) targets receptors for two key hormones GLP-1 and GIP both of which play a role in insulin regulation and satiety

The dosed subjects were chronic insomniacs and patients in alcohol or opiate withdrawal

10.1016/j.bbi.2015.03.016 217 JiangH.ZhangX.YuZ.ZhangZ.DengM.ZhaoJ.et al

185,259 Other possible side effects include drowsiness, fatigue, weight gain, headache, and unstableness, as well as suicidal thoughts in rare cases