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Study two In a 1997 study, 11 men aged 64-76 received nightly injections of 2mg sermorelin for six weeks

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Methods: We searched the Web of Science, Cochrane Central Register of Controlled Trials, PubMed, PsycINFO, and Scopus for relevant Randomized Clinical trials (RCTs) from inception until 1 August 2022

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However, realistic expectations matter: semaglutide monotherapy produces an average 15-22% body weight reduction over 68 weeks in clinical trials, which is substantial and sustainable when combined with lifestyle changes

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