In the context of DR, this leads to the phosphorylation of ERK1/2, increasing downstream expression of anti-apoptotic genes like BCL2 and reducing the activity of pro-apoptotic markers such as Caspase-3
doi: 10.1210/en.2014-1685 21 KaschinaEUngerT
Incorporating more of these into your diet can give you an extra boost
We are a community of individuals with various needs, and it is always most helpful to hear from someone who is going through something similar and can offer a helpful hand
In brief, GLP-1R is found on various immune cells, and the GLP-1R signaling pathway contributes to the regulation of immune cell function
Athletes are not good candidates if: They are chronically under-fueling They have a history of an eating disorder or disordered eating If their nutrition, recovery, and other key lifestyle habits aren't yet well established Athletes may benefit, alongside comprehensive nutrition and medical care, if: They're experiencing overweight/obesity or metabolic disease Have significant inflammation or other medical conditions Have experienced certain peri/post-menopausal changes Even if you're a good candidate for GLP-1 meds, there are still potential risks
