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In mammalian cells, six peroxiredoxins isoforms expressed and localized to various cellular compartments function as a peroxidase and contain an active site cysteine that can be oxidized by H 2 O 2 (Rhee et al., 2012)

doi:10.1016/S0302-2838(02)00354-8

For example, it could mean that you observed no specific immunofluorescence staining at the antibody concentration that we suggested