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However, PROTACs are typically large and highly polar, with molecular weights often exceeding 800 Da---far beyond Lipinski's Rule of Five (Ro5) for orally bioavailable small-molecule drugs
Also helps keep skin balanced and healthy-looking
Fischer L, Peter C, Garg P, Sharp A, Akbarian S, Galler J
This strategy of alternating treatments between each subsequent animal or cage was used to minimise the likelihood of confounding effects
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