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It has been demonstrated that the insulinotropic effect on -cells and glucagonostatic effect on -cells each contribute to about half of GLP-1s blood glucose-lowering activity (134)

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Semaglutide treatment over four months led to a weight reduction of 5 kg, from 118 kg (BMI 55 kg/m 2 ) to 113 kg (BMI 52.7 kg/m 2 )

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Another complication that can be associated with Becker melanosis is breast hypoplasia, which involves unequal breast development

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