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Proof of concept: effect of GLP-1 agonist on food hedonic responses and taste sensitivity in poor controlled type 2 diabetic patients
Overactivation of either pathway can result in disease and downregulation of other pathways
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The goal is to achieve effective appetite control and weight loss while significantly minimizing potential side effects for a more comfortable experience
They also play a key role in the operations of the central and peripheral nervous systems
doi: 10.1056/NEJMoa2032183 22 PratleyREArodaVRLingvayILudemannJAndreassenCNavarriaAet al
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