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Absence of functional BLM protein can cause increased rates of pathogenic variants and recombination

In series of complex degradation reactions of hydro- and dihydro-peroxides of polyunsaturated fatty acids, many other aldehydes are produced: 4-hydroxy-alkenals, 4-hydroperoxy-alkenals, 4-oxo-alkenals and bis-aldehyde malonaldehyde (MDA) 28

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"Decline of neural tube defects cases after a folic acid campaign in Nuevo Leon, Mexico." Teratology 66(5): 249-256