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[2] Pharmacokinetic studies demonstrate rapid systemic distribution with peak plasma levels occurring within 30-60 minutes of intramuscular injection, followed by extensive hepatic storage and enterohepatic recycling

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I have self injected upper arms for the last three or so years now,Ive did hundreds of injections and the only time I feel pain is if Im lucky enough to have a nurses appointment,other than that I feel totally in control of any pain risks and although I admit I still hate doing them its not because its painful its just needle phobia in my case

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