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Notably, the addition of liraglutide to metformin reduces EAT by nearly 40%, with approximately 30% of this reduction achieved as early as 3 months after treatment initiation (163)

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The 98-participant trial used liver fat content, assessed by MRI-derived proton density fat fraction (MRI-PDFF), as the primary endpoint at 24 weeks

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Given the increasing interest in the potential use of incretins in cardiovascular diseases, conducting randomized controlled trials in this direction is warranted

SalB exhibits multiple features of anti-oxidant, inflammation inhibition, and immune modulation, which are indispensable for the treatment of PF (Ho and Hong, 2011)