It contributes to normal red blood cell formation, supports nervous system health, and plays an important role in energy metabolism and reducing tiredness and fatigue
All participants had a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related comorbidity
Systemic lupus erythematosus (SLE) and rheumatoid arthritis have been noted in case reports
Oral and injectable B12 are both effective
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Conclusions Ultimately, the current maintenance dose of 1,000 mcg B12 every 3 months may confer long term harm, therefore it seems that once B12 levels are stabilised well within acceptable range, then the standard B12 intervention of 1000 mcg should be administered annually, and monitored with pre-injection annual testing of levels
