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These metabolic changes lead to glomerular hyperfiltration, enlargement, and increased proximal tubular glucose reabsorption via sodium-glucose cotransporter 2, resulting in elevated intraglomerular pressure and hyperfiltration [25]

Its antioxidant properties make it a key player in the body's defense against oxidative stress and inflammation

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But it can also be prescribed off-label for weight reduction because substantial evidence supports its effectiveness

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