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99-101 Some evidence suggests long-term berberine use, especially at high doses, may impair some aspects of cellular metabolism in specific types of cells

Its deficiency can result in neurological symptoms like tingling, numbness, and difficulty with coordination

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Patient-reported outcomes (PROs) and biomarker assessments in daNIS-3, a phase II platform study of NIS793 (antiTGF- monoclonal antibody) and other investigational drug combinations with standard of care (SOC) vs SOC alone in patients (pts) with second-line metastatic colorectal cancer (mCRC)

She points to the efficacy of GLP-1s like Ozempic as an example, a peptide with FDA approval that has been found in early research to be even more effective when used in conjunction with estradiol-based hormone replacement therapy