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The enzyme GCL can catalyze the entire reaction to synthesize glutathione, but the presence of the GS enzyme can increase the rate of glutathione formation [23]

Statistical analysis Statistical analyses were performed using SPSS Statistics 18.0 (Chicago, IL, USA)

Understanding what to expect during the adjustment period helps patients distinguish normal adaptation from concerning symptoms

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Its a two-way street in IBD, with the gut microbiome changes potentially causing high homocysteine, but then high homocysteine will increase the inflammation in the gut.[ref] Gastrointestinal production of homocysteine: Gut microbes that produce folate: The amount of folate produced by the gut microbiome is on a similar scale to what we get from food, so it is a significant source of folate for most people