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The resultant B2M-CuS NPs can eliminate senescent chondrocytes via a peroxidase-like activity that converts H 2 O 2 into toxic OH and accelerates apoptosis

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If gastrointestinal symptoms are problematic, your provider may recommend delaying dose increases, temporarily reducing your dose, or holding treatment briefly while symptoms improve

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By targeting both GLP-1 and GIP pathways, tirzepatide produces stronger appetite suppression and improved metabolic control