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These effects were more noticeable in longer trials and when ALA was combined with dietary changes.29 A 2020 dose-response meta-analysis confirmed small but statistically significant reductions in weight and BMI across 18+ randomized controlled trials.30 However, waist circumference (WC) a marker of central obesity showed no consistent change, and the benefit appeared greater in women and with longer treatment durations
Six Months: Patients typically reach their target dose (2.4 mg), and weight loss continues at a steady pace
Umpierrez presented the results of AWARD-3, which involved 807 patients with early type 2 diabetes as evidenced by their mean 2.6-year disease history
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