10.1016/j.cbi.2014.07.007 7 AkakpoJ
Toloza EM, Hunt K, Swisher S , McBride W, Lau R, Pang S, Rhoades K, Drake T, Belldegrun A, Glaspy J, Economou JS
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[19] [21] The compounds targeted in this manner by GSTs encompass a diverse range of environmental or otherwise exogenous toxins, including chemotherapeutic agents and other drugs, pesticides, herbicides, carcinogens, and variably-derived epoxides
In addition, the microplastic also contains a large number of environmental pollutants that adhere to the surface which leads to hazardous effects on organisms ( The glutathione S-transferases (GSTs, EC 2.5.1.18) comprise a supergene family of phase II detoxification enzymes that shield cells against the toxicity of many environmental toxins by enhancing reduced glutathiones (GSH) nucleophilic assault ( To characterize microplastic toxicity and link it to the organismal level of response, the molecular interactions between the microplastic and the biological target must be determined
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