Life in this twenty-first century is not as that many thousands years ago, but there are always a lot of stressful events that can trigger our hypothalamus and omeostatic system(s) and induce a blockade of reproduction
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2009 Mar Khingkan Lertratanangkoon, Chun J Wu, Niramol Savaraj, Mary L Thomas
The observation that higher plasma concentrations of 2 can be achieved after oral delivery than for PZQ, coupled with the greater ex vivo potency of compound 2 , strongly suggest that further optimization will yield an orally bioavailable schistosomicidal agent that will be transformative in the clinical setting
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Considered the least bio-active and thus the least effective for supplementation
