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Primary Handling Editor: Yanina-Yasmin Pesch, in collaboration with the Nature Metabolism team

Risk of bias was rated low for the RCT in most domains [14]

doi: 10.1016/j.annepidem.2025.09.003

Understanding Acid Reflux Before diving deeper into the relationship between semaglutide and acid reflux, its crucial to have a solid understanding of what acid reflux is and how it affects your body

Medical researchers have discovered that semaglutide may reverse the debilitating tissue damage caused by osteoarthritis, the world's most common form of arthritis

Higher-risk features include recent initiation or dose escalation of Mounjaro, active gastrointestinal symptoms such as nausea or vomiting, known gastroparesis, higher maintenance doses, concurrent opioid use, and procedures with inherently higher aspiration risk