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When addressing dimeric protein targets, the ability of dimeric therapeutic agents to antagonize paired receptors within a single molecular entity potentially offers superior therapeutic efficacy and target selectivity 15,16

M.WileyN.StrainC.O'SullivanO.et al

At our clinic, we have worked with patients to find a pharmacy that has it in stock, or in some instances have had to adjust the dose or change between similar medicines

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57 , 168 These approaches can be problematic as high doses are not clearly defined, and because of a lack of tachyphylaxis to gastric emptying effects, short-acting GLP-1 RAs affect gastric emptying more than the long-acting ones

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