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In the human liver microsomes, Deg-AZM, M1-2 (hydroxylation of Deg-AZM), and M2 (demethylation of Deg-AZM) were the main forms of the drug, accounting for 34.4%, 30.0%, and 17.1% of the total related substances, respectively

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Sulforaphane was found to attenuate pancreatic injury in a mouse model of acute pancreatitis by stimulating Nrf2-induced antioxidant enzymes (18)

The loss of redox homeostatic balance in the brain in the presence of increased ROS or reduced GSH and similar antioxidant molecules may suggest a pro-inflammatory aetiology in MDD