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Fumarate Links Metabolism, Immune System Function, and Cancer The major source of fumarate is the TCA cycle but in addition fumarate is generated in the context of the urea cycle, the biosynthesis of the purine nucleotides, and in the catabolism of the amino acids phenylalanine and tyrosine

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Something could have gone wrong with the test itself , though the lab usually detects it if all their tests get unusual results

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