GLP-1
The ERK and JNK are parts of the insulin signal pathway and closely associated with tau hyperphosphorylation
Back Eng, J, Kleinman, WA, Singh, L, et al (April 1992) 'Isolation and characterisation of Exendin-4, an Exendin-3 analogue, from heloderma suspectum venom', The Journal of Biological Chemistry , 267/11, 7402-06
These 3 genes, X box binding protein 1 ( XBP1 ), activating transcription factor 4 ( ATF4 ), and ATF6 , are regulators of the 3 pathways of the unfolded protein response (UPR) (57, 58)
If you have type 2 diabetes and take insulin, GLP-1s could also increase the risk of low blood sugar
Contact us if youd like to learn more about Capital Rxs Clinical Programs or full-service Pharmacy Benefit Solutions