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Urgent Medical Evaluation : Palpitations lasting more than several minutes, occurring with increasing frequency or severity, or accompanied by less severe but concerning symptoms (mild shortness of breath, mild chest discomfort) should prompt urgent medical assessment, typically within 24-48 hours

Key signs include the disproportionate accumulation of fat in the legs, hips, and sometimes arms, along with tenderness or pain in those areas

The first line of defense against superoxide is the presence of a specific member of the family of metalloenzymes called superoxide dismutases (SODs), MnSOD or SOD2, specifically located in the mitochondrial matrix, which catalyzes the dismutation of superoxide anion into H 2 O 2 as shown in Figure 2

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However, it can also cause weight gain, increased blood sugar, and fluid retention

1994 Jun;102(1-2):45-52