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Pycnogenol has been shown to have four main effects being its antioxidative effects (Figure 1)

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Remember, 1 mL is about 1000 mcg

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A physiological role of GLP-1 as an anorectic or satiety factor is suggested due to the observations that intracerebroventricular (i.c.v.) injection suppresses food intake and body weight gain in normal and obese rats