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Sensitivity analysis According to the sensitivity analysis, no study affected the overall results after removing individual study effects

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International Archives of Allergy and Applied Immunology 49:70914

Effects of changes in body weight on carbohydrate metabolism, catecholamine excretion, and thyroid function

Abbreviations BBD: Box-Behnken design BSA: Bovine serum albumin DTNB: (5,5-dithiobis-(2-nitrobenzoic acid) GPx: Glutathione peroxidase GSH: Reduced glutathione GSSG: Oxidized glutathione LOD: Limits of detection LOQ: Limits of quantitation RSM: Response surface modeling TBuOOH: Tert-Butyl hydroperoxide TNB: Nitro-2-thiobenzoate anion WSAVA: World Small Animal Veterinary Associations References Ademi M (2023) The role of ionized water and its impact on the activity of glutathione peroxidase on rats blood serum during hyperthermic stress

Other information lacking in some studies was the identification of diabetic complications (retinopathy, nephropathy, neuropathy), which could have affected the choice of insulin or fracture risk