The antithrombotic properties of GLP-1R agonists are complementary to those offered by platelet antagonists (aspirin, clopidogrel) and are not associated with an increased bleeding risks [99, 100]
Rapid weight loss from any cause increases the risk of gallstone formation, and we do see higher rates of cholelithiasis and cholecystitis in patients on GLP-1 medications, Dr
Lancet (2010) 375(9724):144756
However, in conditions where the GFR is diminished such as kidney diseases, glucosuria may require high plasma glucose levels whereas lower plasma glucose levels are needed when GFR is increased as during pregnancy or Diabetes
For one, it may support weight management by regulating appetite, so people can manage their calorie intake more effectively
However, the study also found that the risk of gallbladder varied between different types of GLP-1 agonists and depended on the therapy duration and dosage