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Melanotan-II Melanotan-I (afamelanotide) and Melanotan-II (MT-2) share structural similarities but differ in stability, receptor selectivity, and side effects

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Moreover, it is well-established that intestinal barrier function is a crucial factor in the protection against allergies and infections, by preventing allergen and bacterial translocation from the gut lumen into the immune cell-populated lamina propria and mesenteric lymph nodes (105107)