At times the needle can hit a small blood vessel causing a small amount of bleeding under the skin This causes a bruise to appear which resolves over a few days
The deficiency was more severe than expected People with advanced B12 deficiency, especially with neurological symptoms, often feel rough at the start of treatment because the underlying problem was significant
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Deficiencies in vitamin B12 can cause fatigue, weakness, and nerve issues
Individuals at higher risk include older adults with reduced stomach acid production, people with gastrointestinal conditions affecting absorption, strict vegans, and those taking medications like metformin or proton pump inhibitors
Clinical Interpretation Several aspects of these results deserve expert-level analysis: The biphasic dose-response is clinically important