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Improvements are gradual over days to weeks as oxidative stress levels decline

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Woo JS, Kim W, Ha SJ, Kim JB, Kim SJ, Kim WS, et al

In the intestine, we detected the protein levels of PC1/3 and PKA by Western blot (Figure 4G), and found that the expression of PC1/3 and the phosphorylation level of PKA increased after the treatment of berberine (Figures 4H, I)