Serious adverse events are rare but include pituitary axis suppression with long-term high-dose use and worsening insulin resistance in patients with pre-existing glucose issues
Its very complete formula combines an impressive collection of powerful antioxidant ingredients : purified lutein (against blue light), soothing superoxide dismutase, pycnogenol, tomato carotenoids (which give it its brown-orange color), and dimethylmethoxy chromanol, an antioxidant ingredient more effective than resveratrol according to the brand
However, many people report positive results, suggesting it may be an effective skin-lightening option
This can be another sign that the dosage is too high and should be reduced.
J Clin Endocrinol Metab (2005) 90:6498507
This drop is what brings on menopause symptoms like hot flashes and vaginal dryness