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Lee JW, Gu HO, Jung Y et al (2023) Candesartan, an angiotensin-II receptor blocker, ameliorates insulin resistance and hepatosteatosis by reducing intracellular calcium overload and lipid accumulation

Microbiota can directly or indirectly affect mitochondria

Expression of hepatic insulin-like growth factor-I and insulin-like growth factor-binding protein-1 genes is transcriptionally regulated in streptozotocin-diabetic rats

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They can be injected in the same session (separately drawn up, separate syringes), but never mix in the same vial