The rates are remarkably similar across all three, despite their different mechanisms: Semaglutide: Nausea approximately 18%, diarrhea approximately 12%, vomiting approximately 8% Tirzepatide: Nausea 17-22% (dose dependent), diarrhea 13-16%, vomiting 6-10% Retatrutide: Nausea 16-25% (dose dependent), diarrhea 15-22%, vomiting 8-13% The pattern holds consistently
Food and Drug Administration (FDA) to promote blood sugar control in adult patients with type 2 diabetes when paired with a healthy lifestyle, such as dietary modifications and exercise
Our semaglutide to tirzepatide dose conversion chart goes deeper into the clinical reasoning
And she says shes in a better place than shes been in years
Therapies that offer better efficacy could be saved for sicker diabetic patients
I have a framework for deciding which one to start with, and it goes beyond the one with more weight loss wins. Heres how I think about it