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Conclusion Looking ahead to diabetes care in 2026, the role of metformin is being reconsidered but not abandoned

comparing metformin, liraglutide, and combination therapy (metformin 1000 mg BID + liraglutide 1.2 mg/day), the latter, and not liraglutide 1.2 mg/day alone, was superior to metformin alone in reducing glucose levels at 120 min during OGTT [61]

PMID: 24045836

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Some studies have found that GLP-1RAs may play an anti-osteoporotic effect by controlling blood sugar levels, promoting bone formation and inhibiting bone resorption