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Chronic activation of the hypothalamic-pituitary-adrenal (HPA) axis leads to prolonged elevation of cortisol, which can downregulate serotonin and dopamine receptor expression in areas such as the prefrontal cortex and limbic system, contributing to mood disorders and impaired cognitive function

We must consider the full spectrum of patients culture, trauma, mental health, structural advantages and disadvantages, lifestyle, and economic resources when considering which medications can effectively address their addiction in a long-term, sustainable way that benefits overall health and restores agency

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Patients should avoid self-treating with peptides purchased from unknown suppliers

This is a delicate chemical structure, and being aggressive can damage it